Fig. 8: Mechanistic studies.
From: Cobalt-catalyzed atroposelective C−H activation/annulation to access N−N axially chiral frameworks
a H/D Exchange experiments using 1a or [D5]−1a as substrates. b Parallel and competitive kinetic isotope experiments to calculate KIE values. c Nolinear effect study between the enantiomeric excess (ee) of product 3aa and the ee of L6. d Plausible mechanism for the Co/Salox catalyzed annulation.
