Fig. 5: Taurinivorans muris is the dominant sulfidogen in wild-mouse-microbiota-derived wildR mice that provided H2S-mediated protection against Klebsiella pneumoniae.
From: Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut
Re-analysis of mouse gut metagenome and 16 S rRNA gene amplicon data from Stacy et al.37. a Identity and relative abundance of dsrAB-encoding taxa in different mouse models. Relative abundance was calculated with mapped dsrA and dsrB read counts. Samples with less than ten total mapped read counts were not displayed. Each column shows a sample from an individual mouse. Taurine-treated mice: specific-pathogen-free (SPF) mice that received taurine in drinking water and showed enhanced resistance to Klebsiella pneumoniae and Citrobacter rodentium; ΔyopM mice: SPF mice that were previously infected with the attenuated strain ΔyopM of the food-borne pathogen Yersinia pseudotuberculosis and showed enhanced resistance to K. pneumoniae; SPF mice were used as control for taurine-treated and ΔyopM mice; lab mice: laboratory SPF mice; wild mice: wild-caught mice; F2 LabR mice: the second generation offspring of SPF mice whose germ-free founders received the microbiota of labR mice; F2 wildR mice: the second generation offspring of SPF mice whose germ-free founders received the microbiota of wild mice and showed enhanced resistance to K. pneumoniae. b Relative 16 S rRNA gene abundance of Desulfovibrionaceae species in the 2nd (animal. Ordinary one-way ANOVA with Holm-Sidak’s multiple comparisons test, *p < 0.05. Source data are provided as a Source Data file.
