Fig. 3: Synthesis of silicon-stereogenic optically active silylboranes and disilanes. | Nature Communications

Fig. 3: Synthesis of silicon-stereogenic optically active silylboranes and disilanes.

From: Stereospecific synthesis of silicon-stereogenic optically active silylboranes and general synthesis of chiral silyl Anions

Fig. 3

aConditions for the borylation system: 1 (0.3 mmol), Pt(PPh3)4 (2 mol%), B2(pin)2 (0.75 mmol) in cyclohexane (0.3 mL) at 80 °C; conditions for the Si–Si bound formation reaction: 2 (0.1 mmol), MeLi (1.2 M in Et2O; 0.15 mmol), chlorosilane (0.2 mmol) in THF (0.5 mL). The yield values refer to isolated yields. The ee values were determined by chiral HPLC. bPresumed ee value. c(+)-(R)-2b with methyllithium in THF at –78 °C for 30 min.

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