Fig. 2: Phylogenetic analysis reveals known and novel lineages of C. tetani in ancient DNA samples, as well as a previously unidentified Clostridium species (“X”). | Nature Communications

Fig. 2: Phylogenetic analysis reveals known and novel lineages of C. tetani in ancient DNA samples, as well as a previously unidentified Clostridium species (“X”).

From: Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains

Fig. 2

a Dendrogram depicting relationships of acBins from ancient samples with modern C. tetani genomes. Novel branches are labeled “X” and “Y”, which are phylogenetically distinct from existing C. tetani genomes. Shown on the right of the dendrogram are metadata and statistics associated with each acBin including the estimated date of the associated archeological sample. All metadata can be found in Supplementary Data 2. b Geographic distribution of ancient DNA samples from which the 38 acBins were identified. Each sample is colored based on the acBin clustering pattern shown in (a). The global map was derived from the Natural Earth [https://www.naturalearthdata.com/] medium-scale data and plotted using the rnaturalearth and ggplot2 R packages. c SNP-based phylogenetic tree of a subset of acBins from lineage 1 and 2 showing high similarity and coverage to the C. tetani reference genome. See Supplementary Fig. 9 for more details. Source data for (a, c) are provided as a Source Data file.

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