Fig. 3: 6-OAU binding in GPR84.
From: Pro-phagocytic function and structural basis of GPR84 signaling
a Occluded binding pocket for 6-OAU covered by ECL2. The lower panel indicates the charge potential of the 6-OAU binding pocket. The bar shows the levels of negative (red) and positive (blue) charge potential. b Mutagenesis data using GTPγS incorporation assays. Data represent mean ± S.E.M. from at least three independent experiments. c Interactions between 6-OAU and GPR84. The polar interactions are shown as dashed lines. 6-OAU is shown as orange sticks in all figures.
