Fig. 1: Description of each type of clonal hematopoiesis (CH).
From: Shared and distinct genetic etiologies for different types of clonal hematopoiesis
The top panel depicts the acquisition and clonal expansion of a CH clone and its potential for elevated hematologic cancer risk. Lower panels illustrate loss of chromosome Y (LOY); loss of chromosome X (LOX); autosomal mosaic chromosomal alterations (mCAs) that include (A) genomic deletions, (B) copy neutral loss of heterozygosity (CNLOH), and (C) genomic duplications; clonal hematopoiesis of indeterminate potential (CHIP); and myeloproliferative neoplasms (MPN).
