Fig. 5: Stacked Manhattan plots from the Multi-Trait Analysis of genome-wide association study (GWAS) summary statistics (MTAG) and colocalization analyses among telomere length, LOY, and MPN (Top plot) and the original MPN GWAS performed by Bao et al. (Bottom plot). | Nature Communications

Fig. 5: Stacked Manhattan plots from the Multi-Trait Analysis of genome-wide association study (GWAS) summary statistics (MTAG) and colocalization analyses among telomere length, LOY, and MPN (Top plot) and the original MPN GWAS performed by Bao et al. (Bottom plot).

From: Shared and distinct genetic etiologies for different types of clonal hematopoiesis

Fig. 5

Nominated MPN susceptibility loci are labeled by analysis, MTAG(stars, ★), loss of chromosome Y (LOY) colocalization (circles, ●), TL colocalization (squares, ◼), and colored red for previously unidentified and black for previous identified. Supporting data for MTAG signals are defined in Supplementary Data 23 and data for colocalization analyses is available in Supplementary Data 24 and 25.

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