Fig. 7: Hypothetical model for the PR-1La function.
From: Ustilago maydis PR-1-like protein has evolved two distinct domains for dual virulence activities
Upon host entry, U. maydis employs UmPR-1La to sense phenolics, initiating signals for shielded hyphal branching as a defense against toxic phenolics. This sensing mechanism promotes fungal hyphal growth towards phenolic-enriched vascular bundles. Additionally, the exposure of UmCAPE-La on the cell surface facilitates its cleavage by CatB3 and subsequent release. UmCAPE-La presumably competes with ZmCAPE for binding to an unidentified receptor, suppressing plant immunity and enhancing U. maydis virulence. Created with BioRender.com.
