Fig. 4: PROCR expression pattern in Normal-Healthy, NATs, and breast tumors.

a Representative IHC of PROCR in Normal-Healthy, NATs, and/or tumors of women of AA and EA. b Enlarged view of PROCR expression in Normal-Healthy and tumor. c Differences in PROCR expression (positivity and H-score) between Normal-Healthy tissues of women of AA and EA. Differences in PROCR expression (positivity *p = 2.2051E−8 and H-score *p = 6.0538E−9) between Normal-Healthy tissues of AA and EA. The statistical test that was utilized to analyze the data was two-sided Wilcoxon Test. d Differences in PROCR expression (positivity and H-score) between Normal-Healthy and NATs of women of AA and EA (positivity *p = 4.588E−11 and H-score *p = 1.4572E−11). The data were analyzed using two-sided Wilcoxon test. e Differences in PROCR expression (positivity and H-score) between NATs and tumors of women of AA and EA. Data were analyzed using two-sided Wilcoxon test. (Normal-Healthy-AA (n = 31), and EA (n = 129); NAT -AA (n = 35) and EA (n = 31); Tumor -AA (n = 41) and EA (n = 62)). Depending on availability, two cores of same NAT and tumor were included in the TMA. Dot blots in this and subsequent relevant figures include values from both cores of the same sample. All the data points are shown as mean ± SD. Source data are provided as a Source Data file.