Fig. 2: Phylogenomic analysis of C. glabrata strains from blood cultures of patients with bloodstream infections.

a Unrooted phylogenomic tree of the 94 BSI strains and reference strain CBS138, as estimated using Maximum Likelihood with RaxML. It is based on a genome alignment generated from variant calling data. Within-patient diversity is demonstrated for all strains, in each patient. Strains from a given patient are color coded and sequence type is shown to the right. b Unrooted phylogenomic radial tree built with parsimony using PAUP is shown for each of 10 strains from 4 representative patients. Each patient was infected with a different C. glabrata ST. Also shown are Venn diagrams of numbers of genome variants, comparing 5 C. glabrata strains from individual patients.