Fig. 5: Hypothesized ligand transformation in the BNC during the CcO reaction cycle.
From: Structural insights into functional properties of the oxidized form of cytochrome c oxidase

The oxidative and reductive phase of the reaction cycle are highlighted with green and blue backgrounds, respectively. The white arrows indicate the proton translocation reactions associated with the reaction cycle. The lifetimes associated with the PR→F, F→OH and OH→O transitions are indicated in red.