Fig. 4: Cellular communication landscape between immune cells and cutaneous cells.
From: Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration
a Schematic timeline highlighting the recruitment of immune cells from innate and adaptive immune systems in Ctrl_LW (top) and ECM_LW (bottom) groups. b Comparison of overall cell-cell interaction numbers of immune cells and cutaneous cells between Ctrl_LW and ECM_LW using CellChat. c The ligand–receptor pairs up-regulated in the Ctrl_LW group in specificity between AIM1 and fibroblasts (MF1, RF1, and LF1). d The ligand–receptor pairs up-regulated in the ECM_LW group in specificity between Treg1, MAC (Mono1, PIM1, AIM1), and HFSC1. e Spatial feature plots and corresponding violin plots showed the expression level of the ligand and cognate receptor in the Notch signaling pathway.
