Fig. 5: Re-analysis of putative RNA modification induced variants identified by ModTect with Spiked iMVP. | Nature Communications

Fig. 5: Re-analysis of putative RNA modification induced variants identified by ModTect with Spiked iMVP.

From: Epitranscriptomic subtyping, visualization, and denoising by global motif visualization

Fig. 5

a The diagram showing the Spiked iMVP strategy used in ModTect dataset analysis. b–e The global visualization of ModTect variants with A, U, C, and G as the reference base. The spiked sequences with known modifications, as well as the manually checked variants reported by Tan et al.11, were shown as red asterisks. The motifs and the number of spike-in sites against total sites were also shown. 2522, 1912, 1564, and 7225 sites were analyzed separately.

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