Fig. 7: In vivo protective effect. | Nature Communications

Fig. 7: In vivo protective effect.

From: Biomimetic single Al-OH site with high acetylcholinesterase-like activity and self-defense ability for neuroprotection

Fig. 7

a Schematic illustration of the OP-damaged model mice and the MOF-808-Al-mediated treatment. b Mice weight after treatment with saline, DENP, MOF-808-Al, and MOF-808-Al + DENP for 8 days. Data are represented as mean ± s.d. (n = 4 independent mice). c Relative activity of AChE in the serum of mice after various treatments. Data are represented as mean ± s.d. (n = 4 independent serum of mice). H&E staining d hippocampus and e liver and kidney after different treatments. The level of f MDA, g GSH, h SOD in liver tissues of mice, and i the level of ALP in the serum of mice after different treatments. Data are represented as mean ± s.d. (n = 3 independent serum of mice). Statistical significance is assessed by the Student’s two-tailed test. Source data are provided in the Source Data file.

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