Fig. 3: Relative Risk Calibration of PRS.

The relative risk calibration of PRS, stratified by race and ethnicity, using N = 120,25; 9756; 10,377 and 80,542 of unrelated samples of Asian, Black or AA, Hispanic and non-Hispanic White, respectively. The x-axis is the log-transformed predicted RR values and the y-axis is the log-transformed observed RR +/− 1.96 standard error with the middle bin (40–60) as the reference group.