Fig. 4: Gene expression in lung and peripheral blood mononuclear cells (PBMCs).

a The consensus transcript expression levels summarized per gene in 54 tissues in Human Protein Atlas (HPA), which was calculated as the maximum transcripts per million value (TPM) value for each gene in all sub-tissues categories of each tissue, based on transcriptomics data from HPA and GTEx. The consensus transcript expression level for PMF1 was not available in HPA. b RNA single cell type tissue cluster data (transcript expression levels summarized per gene and cluster) of lung (GSE130148) and peripheral blood mononuclear cell (PBMC) (GSE112845) were visualized using log₁₀(protein-transcripts per million [pTPM]) values. Each c-X annotation is taken from the clustering results performed in HPA. c Single-cell RNA expression profile of 23 lung COVID-19 autopsy donor tissue samples from GSE171668²⁰. The RNA expression of PMF1 was not detected in this dataset. The mean value of RNA expression of the cells annotated in the same subcategory was represented as a dot per each sample. The cell type annotation was manually performed in the original publication. AT1 alveolar type 1 epithelial cells, AT2 alveolar type 2 epithelial cells, EC endothelial cells, KRT8⁺ PATS/ADI/DATPs KRT8⁺ pre-alveolar type 1 transitional cell state, MAST mast cells, XXhi XX (gene expression) ^high cells, RBC red blood cells. Lower edge of the whisker: the lowest value within 1.5 * IQR of the hinge, lower hinge: 25% quantile, horizontal line contained within the box: median value, upper hinge: 75% quantile, the upper edge of the whisker: the highest value that is within 1.5 * IQR of the hinge.