Table 1 Lifetime burden of tuberculosis stratified by RS-TB and RR-TB, globally and per incident tuberculosis case, 2020

From: Global burden of disease due to rifampicin-resistant tuberculosis: a mathematical modeling analysis

Form of disease

Outcome

TB disease

Post-TB

Total

Total global DALYs (millions)

RS-TB

YLLs

63.5 (55.5, 72.1)

39.7 (25.6, 57.9)

103.2 (86.4, 122.2)

YLDs

4.9 (2.5, 8.3)

14.5 (8.3, 23.5)

19.4 (12.4, 28.5)

DALYs

68.4 (59.7, 77.6)

54.2 (35.6, 79.7)

122.6 (100.8, 149.0)

RR-TB

YLLs

3.6 (3.1, 4.3)

2.2 (1.3, 3.2)

5.9 (4.8, 7.1)

YLDs

0.2 (0.1, 0.3)

0.9 (0.4, 1.4)

1.1 (0.6, 1.6)

DALYs

3.8 (3.2, 4.4)

3.1 (1.8, 4.4)

6.9 (5.5, 8.5)

All disease

YLLs

67.1 (58.8, 76.1)

42.0 (27.6, 60.7)

109.1 (91.9, 128.9)

YLDs

5.1 (2.6, 8.6)

15.3 (8.8, 24.7)

20.4 (13.1, 29.9)

DALYs

72.2 (63.2, 81.9)

57.3 (37.7, 83.5)

129.5 (107.1, 156.9)

DALYs per incident tuberculosis case

RS-TB

YLLs

6.7 (5.9, 7.5)

4.2 (2.8, 6.0)

10.9 (9.3, 12.7)

YLDs

0.5 (0.3, 0.9)

1.5 (0.9, 2.5)

2.0 (1.3, 3.0)

DALYs

7.2 (6.4, 8.0)

5.7 (3.7, 8.4)

12.9 (10.8, 15.6)

RR-TB

YLLs

9.1 (7.6, 10.5)

5.6 (3.3, 7.8)

14.6 (12.0, 17.1)

YLDs

0.5 (0.2, 0.8)

2.1 (1.1, 3.3)

2.6 (1.6, 3.9)

DALYs

9.6 (8.1, 11.0)

7.7 (4.5, 10.7)

17.3 (13.8, 20.6)

All disease

YLLs

6.8 (6.0, 7.6)

4.2 (2.8, 6.1)

11.0 (9.4, 12.8)

YLDs

0.5 (0.3, 0.9)

1.5 (0.9, 2.5)

2.1 (1.3, 3.0)

DALYs

7.3 (6.5, 8.1)

5.8 (3.8, 8.4)

13.1 (11.0, 15.7)

  1. YLLs ‘years of life lost’ due to fatal disease consequences, YLDs ‘years lived with disability’ due to non-fatal disease consequences, DALYs disability-adjusted life years (the sum of YLLs and YLDs), RR-TB rifampicin-resistant tuberculosis, RS-TB rifampicin-susceptible tuberculosis.
  2. Values in parentheses represent 95% uncertainty intervals.