Fig. 1: Identifying eQTLs in patients with psoriasis.
From: Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin
a PAUSE clinical trial structure and sampling strategy for the individuals used for eQTL analysis. b Heatmap of lesional and non-lesional sample number per subject before and after treatment. c Volcano plot of eQTL effects for the significantly associated SNP for each gene (red color indicates p < 6.7e−9). d Concordance of ITN PAUSE deduplicated lead variant-gene pairs with significant eQTLs observed in the GTEx consortium28 (FDR < 0.05) of 449 individuals. Each point represents a significant SNP–gene pair in this study. Concordant pairs are colored in black, discordant pairs are colored in gray.
