Fig. 1: Bacterial species composition and associations among bacterial speices, SCFAs and BMD.
From: Gut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways
a Rarefaction curve: the number of bacterial species (Y-axis) was plotted against the number of samples (X-axis, n = 499). b Bacterial species composition in the study cohort composed of top 10 bacterial species. c−f Bacterial species/SCFAs related to BMD/VA in the Chinese cohort and US cohort by constrained linear regression analysis or multiple linear regression analysis. Regression coefficients (Y-axis) were plotted against independent variables (X-axis). Species/SCFAs and covariates were considered as independent variables and represented by the blue lines. The length of the blue line indicates the 95% confidence interval (CI). c L1-L4 BMD-related species of Chinese cohort (n = 499); d HTOT BMD-related speices of the US white cohort (n = 59); e L1-L4 BMD-related SCFAs of of Chinese cohort (n = 500); f Valeric acid-related species of Chinese cohort (n = 499). Source data are provided as a Source Data file. SCFAs short chain fatty acids, BMD bone mineral density, L1-L4 lumbar spine, HTOT left total hip, YSM years since menopause, BMI body mass index.
