Fig. 5: Structural similarities between Alteromonas phage tail fibers and other tail fibers.

a Ribbon representations of the A5 gp8 fiber model, the R2 pyocin of P. aeruginosa (PDB ID: 6CL6)³⁹ and the distal tip of the putative tail fiber of A. baumannii phage AP22 (PDB ID: 4MTM)⁴⁰ contain similar domain structures as highlighted for their knob (blue box) and distal head (red box) domains. b Superposition of the A5 knob 1 to the pyocin knob 2 domains as generated by DALI³⁸ (Z-score=9.2, RMSD of 2.4 Å (78 residues)). Knob domains of V22 and A5 demonstrate similar levels of similarity (Fig. S3). c Superposition of the head domains from A5 gp8 and V22 gp26 to that of phage AP22 gp53 (Z-scores of 3.6 and 5.3 RMSD of 2.9 and 2.4 Å) that share the lectin-like fold also featured at the tip of the pyocin fiber. Model confidence scores are provided in Table S1. Source Data (.pdb files) are provided as a Source Data file.