Fig. 7: Conceptual representation of the intersection between parasites, immune response and metabolism, in this parasite and mouse strain combination.

a Overall treatment design and expected impacts. b Interactions before antiparasitic treatment. c Interactions after antiparasitic treatment but without therapeutic vaccine. d Interactions after antiparasitic treatment and therapeutic vaccine. BNZ benznidazole, CCC chronic Chagasic cardiomyopathy, LPC lysophosphatidylcholines, PC phosphatidylcholines, MP macrophage, DC dendritic cell. Figure created using BioRender.com.