Fig. 4: PGS associations with TSH/free T4 across non-European ancestries in UK Biobank. | Nature Communications

Fig. 4: PGS associations with TSH/free T4 across non-European ancestries in UK Biobank.

From: Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease

Fig. 4

The TSH PGS association with TSH and free T4 across ancestry groups in UK Biobank shown as standard deviation (SD) change in TSH/free T4 per SD increase in the PGS. The ancestry groups were as defined by the Pan-UK Biobank initiative – AFR African ancestry, AMR admixed American ancestry, CSA Central/South Asian ancestry, EAS East Asian ancestry, MID Middle Eastern ancestry. Error bars indicate 95% confidence intervals. Sample size for TSH: AFR, n = 1430; AMR, n = 249; CSA, n = 3033; EAS, n = 721; MID, n = 479. Sample size for free T4: AFR, n = 584; AMR, n = 145; CSA, n = 1307; EAS, n = 362; MID, n = 256.

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