Fig. 5: Association of TSH PGS deciles with thyroid diseases.

The TSH PGS decile analysis for four clinical thyroid phenotypes—(a, top left) hypothyroidism, (b, top right) hyperthyroidism, (c, bottom left) thyroid cancer, and (d, bottom right) other thyroid disease. Statistical tests were two-sided, the height of the bars show the point estimate of the effect and whiskers show the 95% CI. OR odds ratio. The Mann-Kendall test is a test for monotonic trend. Sample size: Hypothyroidism, 29,550 cases and 368,691 controls; Hyperthyroidism, 5549 cases and 392,692 controls; Thyroid cancer, 624 cases and 358,144 controls; Other thyroid disease, 1233 cases and 124,515 controls.