Table 1 Demographics

From: The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases

 

Controls

PD

DLB

MSA

PSP

AD

Ataxia

N

8

8

2

13

3

5

3

Age

63 ± 11

68 ± 6

81 ± 1

61 ± 8

72 ± 9

69 ± 4

54 ± 14

Sex (M/F)

5/3

7/1

2/0

7/6

3/0

4/1

2/1

Injected dose (MBq)

314 ± 39

308 ± 56

289 ± 1

297 ± 13

298 ± 8

296 ± 5

267 ± 67

UMSARS I + II

–

–

–

53 ± 23

–

–

–

UPDRS-III

–

65 ± 16

–

–

–

–

–

Hoehn&Yahr

–

2 ± 0

2 ± 0

3.5 ± 1.2

4 ± 0

–

–

Number with dynamic data (number with arterial input function)

8 (7)

6 (5)

2 (2)

9 (8)

–

–

–

  1. Demographic data of participants. Ataxia includes three participants with hereditary ataxia, two with Friedreich Ataxia and one with a mutation in the SAMD9L gene.
  2. AD Alzheimer’s dementia, DLB dementia with lewy bodies, F female, M male, MSA multiple system atrophy, PD Parkinson’s disease, PSP progressive supranuclear palsy, UMSARS unified MSA rating scale, UPDRS-III unified PD rating scale, motor part.
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