Table 1 Demographic and anthropometric characteristics in obese and non-obese subjects included in ex vivo experiments. Data represented as median (IQR) and analysed by two-tailed Mann–Witney U test or Fisher’s Exact test
From: Obesity dysregulates the pulmonary antiviral immune response
Obese (n = 15) | Non obese (n = 15) | P value | |
|---|---|---|---|
Age | 46 (30–52) | 37 (30–50) | 0.62 |
Gender (M:F) | 5:10 | 3:15 | 0.68 |
Ethnicity | |||
White British | 11 | 8 | – |
White other | 1 | 5 | – |
Asian | 2 | 1 | – |
Black | 1 | 1 | – |
Height (m) | 1.67 (1.57–1.85) | 1.68 (1.59–1.73) | 0.91 |
Weight (kg) | 144 (112–169) | 61 (56–73) | <0.001 |
Body mass index (kg/m2) | 49.1 (41.0–62.1) | 22.2 (20.6–24.6) | <0.001 |
Skinfold thickness - biceps (mm) | 33 (21–38) | 8 (4–10) | <0.001 |
Skinfold thickness - triceps (mm) | 42 (35–53) | 16 (12–20) | <0.001 |
Skinfold thickness - suprailiac (mm) | 41 (37–57) | 17 (11–19) | <0.001 |
Skinfold thickness - subscapular (mm) | 51 (36–61) | 11 (9–17) | <0.001 |
Body circumference - neck (cm) | 42 (39–50) | 36 (34–38) | <0.001 |
Body circumference - mid-upper arm (cm) | 41 (37–44) | 28 (25–28) | <0.001 |
Body circumference - hip(cm) | 148 (131–160) | 99 (93–107) | <0.001 |
Body circumference - waist (cm) | 126 (119–144) | 76 (70–81) | <0.001 |
FEV1 (L) | 3.07 (2.61–3.20) | 3.20 (2.91–3.67) | 0.17 |
FVC (L) | 3.53 (3.24–3.96) | 4.04 (3.70–4.70) | 0.074 |
FEV1/FVC (%) | 101 (96–105) | 100 (96–105) | 0.67 |
IgE (iU/mL) | 25 (7–66) | 15 (6–33) | 0.44 |
Type 2 Diabetes mellitus | 2 | 0 | 0.14 |
