Fig. 4: CAT, SOD, and APX-like activities of FeN4O2-SACs. | Nature Communications

Fig. 4: CAT, SOD, and APX-like activities of FeN4O2-SACs.

From: Single-atom catalysts-based catalytic ROS clearance for efficient psoriasis treatment and relapse prevention via restoring ESR1

Fig. 4

a Schematic illustration of ROS clearance by FeN4O2-SACs. b ESR spectra of FeN4O2-SACs and natural SOD for O2•- clearance at pH=7.4 (X: xanthine; XO: xanthine oxidase). c Comparison of SOD-like activities between FeN4O2-SACs and control materials CeO2, Mn3O4, Co-SACs, Cu-SACs and Zn-SACs by WST-8 colorimetric analysis. n = 3 independent experiments and data are presented as mean ± SD. d CAT-like assay for eliminating varied concentrations of H2O2 using 125 μg/ml FeN4O2-SACs by UV absorption tests. e CAT-like assay for eliminating 10 mM H2O2 using FeN4O2-SACs of varied concentrations. f Lineweaver‒Burk plots for FeN4O2-SACs and natural CAT at varied concentrations of H2O2 (0-20 mM). g Comparison of the CAT-like activities among FeN4O2-SACs and control materials Mn3O4, CeO2, Co-SACs, Cu-SACs and Zn-SACs. n = 3 independent experiments and data are presented as mean ± SD. h AsA characteristic absorption intensity decreases upon the additions of H2O2 of different samples. i Comparison of the APX-like activities between FeN4O2-SACs and other materials Mn3O4 and CeO2, Co-SACs, Cu-SACs and Zn-SACs. n = 3 independent experiments and data are presented as mean ± SD. Source data are provided as a Source Data file.

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