Fig. 3: Sonodynamic performance of SnSNPs@PEG.
From: Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity
a UV–Vis-NIR diffuse reflectance spectra of SnSNPs. Inset graph shows the corresponding optical bandgap (Eg) of SnSNPs calculated by the Kubelka–Munk equation. b, c Time-dependent oxidation of DPBF by 1O2 generated from US (1 MHz, 1 Wcm−2, 50% duty cycle)-triggered SnSNPs@PEG. d Comparison of DPBF oxidation by US only, SnSNPs@PEG, and SnSNPs@PEG + US. Data are from three independent experiments and are presented as mean ± SD (n = 3). e–g Time-dependent degradation of MB by ·OH generated from US (1 MHz, 2 W cm−2, 50% duty cycle)-triggered SnSNPs@PEG. h Comparison of degradation of MB by SnSNPs@PEG under different treatments. Data from three independent experiments and are presented as mean ± SD (n = 3). i, j Time-dependent degradation of GSH by h+ generated from US (1 MHz, 2 W cm−2, 50% duty cycle)-triggered SnSNPs@PEG. k Comparison of degradation of GSH under different treatments, data are presented as mean ± SD (n = 4). l Mechanism of sonodynamic performance of SnSNPs@PEG under US trigger. GSH, glutathione; GSSG, glutathione disulfide. Illustration was created with BioRender.com.
