Fig. 9: Role of CCZ1 in SARS-CoV-2 infection. | Nature Communications

Fig. 9: Role of CCZ1 in SARS-CoV-2 infection.

From: Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

Fig. 9

a Relative level of infection of CCZ1 KO A549 cells by SARS-CoV-2. Error bar represent mean ± SD. n = 3 independent experiments. Two-tailed Student’s t-test b Western blot analysis of CCZ1 protein expression in siRNA transfected Vero E6. Uncropped blots in Source Data. c Relative level of infection and d inhibition of CCZ1 knocked down Vero E6 cells by SARS-CoV-2. Error bar represent mean ± SD, n = 3 biologically independent replicates. *P < 0.05, **P < 0.01; Two-tailed Student’s t-test. e Relative level of infection and f inhibition of CCZ1 KO Vero E6 cells by SARS-CoV-2. Error bar represent mean ± SD, n = 3 biologically independent replicates. **P < 0.01; Two-tailed Student’s t-test. Exact p values. Source data are provided as a Source Data file.

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