Fig. 4: Selectivity of air puff-responsive pyramidal cells to the type and saliency of the stimulus.
From: Aversive stimulus-tuned responses in the CA1 of the dorsal hippocampus
a Peri air puff (AP, n = 336, 5 session, left panel), peri tail shock (TS, n = 336, 5 session, middle panel) and peri tone (TN, n = 273, 4 session, right panel) firing histograms of putative pyramidal cells and average histograms of significantly activated cells. Shaded areas correspond to s.e.m. b Representative responses of two cells, cell1 responded to air puff and not to tail shock, cell2 responded to tail shock and not to air puff. c Percentages of AP and TS responsive putative pyramidal cells (n = 336, 5 session). nTS-aAP-Pyr, n = 61 air puff-activated but tail shock non-responsive; TS-aAP-Pyr, n = 26 both TS and AP activated putative pyramidal cell; TS-nAP-Pyr, n = 80 tail shock responsive but air puff nonresponsive putative pyramidal cell; nTS-nAP-Pyr n = 169 nonresponsive cell to either tail shock or air puff. d Representative location-lap raster (upper plot) and mean tuning curves during no stimulation and stimulation epochs (lower plots) of a reward (RW) cell. Blue bars mark reward locations, arrowhead and violet bars mark air puff locations. White dashed lines separate consecutive control and air puff (4) epochs. Peri-RW firing histograms in control and air puff epochs are plotted below the location-lap number raster. e Average peri-reward (1st reward upper panel, 2nd reward middle panel) and peri-air puff (lower panel) firing histograms of putative pyramidal cells exhibiting significant activation before (n = 5 from 10 sessions, left panel) or after reward delivery (n = 5 from 10 sessions, right panel). Shaded areas correspond to s.e.m. Markanday, Akshay. (2020). Reward Water Drop. Zenodo. https://doi.org/10.5281/zenodo.3925935.
