Fig. 2: Binding and Dissociation Lifetimes of the Target Capture Complex Events.
From: DNA strand breaks and gaps target retroviral intasome binding and integration
a The TCC binding lifetime (τon) and (b) lifetime of the dissociated state (τoff) for different target DNA substrates. Bars represent the mean, and error bars represent the standard deviation from the fittings of dwell time distributions (Supplementary Fig. 8). c Normalized smFRET histograms and Gaussian fits (Supplementary Tables 3 and 4) showing the FRET distribution for the 1nt Gap (5’-OH) DNA with or without blocking the open DNA end. The binned data, single exponential decay fits, and number of molecules (N) for each substrate DNA examined are shown in Supplementary Fig. 8. Source data are provided in the Source Data File.
