Fig. 1: Factors enriched and depleted at transcription-replication conflicts (TRCs). | Nature Communications

Fig. 1: Factors enriched and depleted at transcription-replication conflicts (TRCs).

From: The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts

Fig. 1

a Schematic summary of the ChIP-seq data downstream processing for enrichment/depletion analysis at TRCs. b Scatter plot indicating the fold change in content for each factor when comparing the TRC site versus its upstream and downstream sequences. c Percentage of factors enriched and depleted at TRCs for each of the GO categories analyzed. d Schematic chart with the most relevant chromatin factors found enriched at TRCs. Bold text is used to highlight gene subcategories. TRC transcription-replication conflict, RF replication fork. The arrow under RF indicate replication fork directionality. Source data are provided as a Source data file. See also Supplementary Figs. 1 and 2.

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