Fig. 5: Characterization of the immune cell subpopulations identified by Mowgli in TEA-seq data.
From: Paired single-cell multi-omics data integration with Mowgli
A UMAP visualization of Mowgli’s embedding with focus on four specific immune subpopulations (Effector Memory CD8 T-cells, memory B cells, CD56dim NK cells, naive B cells) for which the UMAP is colored based on factor weights; B UMAP visualization of Mowgli’s embedding colored by factor weight and protein marker weight for other factors corresponding to specific subpopulations of cells; C Top genes, proteins, gene sets and Transcription Factors (TFs) for the 4 factors visualized in panel a. Stars denote gene sets and markers pertinent for the immune subpopulation associated with the factor and TFs targeting the top genes.
