Fig. 3: IL25 does not enhance thymus regeneration.

a Injection regime for the administration of recombinant IL25 (rIL25), 2.5μg/mouse/injection or PBS control. Three injections were given prior to sub-lethal irradiation (SLI) (1 × 425 rad) and one injection post-SLI exposure. Mice were harvested either 7 or 35 days after SLI. b Effects of IL25 administration on TEC recovery at analysis 7 days post-SLI, and TEC and thymocyte recovery at 35 days post-SLI (c). For (b), PBS and rIL25 n = 8 animals obtained over 2 independent experiments. For (c), TEC PBS and rIL25 n = 8 and thymocytes PBS and rIL25 n = 8 animals obtained over 2 independent experiments. All bars show mean ± SEM. P-values were obtained using two-tailed, unpaired Student’s t tests.