Fig. 4: Fibril protein heterogeneity adjacent to the internal disordered segment.

a Systemic ATTR amyloidosis. Overlay of stick representation of ATTR V30M amyloid fibrils from two patients (PBD: 6SDZ²² and 7OB4³⁰). b Systemic AL amyloidosis. Overlay of two lambda light chain-derived amyloid fibril structures from patient FOR005 (PDB: 6Z1O and 6Z1I)²⁶.