Fig. 1: Design of cell-printable peptide hydrogel platform to produce self-renewable VEGF 165 for diabetic wound healing. | Nature Communications

Fig. 1: Design of cell-printable peptide hydrogel platform to produce self-renewable VEGF 165 for diabetic wound healing.

From: A click chemistry-mediated all-peptide cell printing hydrogel platform for diabetic wound healing

Fig. 1

A Synthetic routes of γ-PGA-GMA and γ-PGA-SH. RT, room temperature. B Chemical structure of RGDC, which presents additional thiol groups compared to RGD. C One-step generation of all-peptide hydrogels using thiol-ene click reaction of γ-PGA-GMA with γ-PGA-SH and RGDC. LAP, a type of photoinitiator stimulated by blue light. D Transfection of VEGF 165 transcript-carried lentivirus in HUVECs for overexpressing VEGF 165. E Printing the HUVECvegf165+-laden peptide hydrogels for diabetic wound healing using sustained-release VEGF 165.

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