Fig. 3: Volcano plot of effect sizes (X-axis) and −log10p (Y-axis) for the 730 proteins tested for breast cancer risk in the Mendelian randomisation analysis. | Nature Communications

Fig. 3: Volcano plot of effect sizes (X-axis) and −log10p (Y-axis) for the 730 proteins tested for breast cancer risk in the Mendelian randomisation analysis.

From: Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Fig. 3

Mendelian randomisation analysis on breast cancer risk in the BCAC study was performed by modelling exposure to genetically higher plasma levels of 730 proteins with at least one cis-pQTL. The Y-axis shows the −log10 p-value of the Wald-score or IVW and the X-axis shows the beta-estimates of the MR result for each protein that was tested.

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