Fig. 2: Spatial proteomic maps of AT/RT tumour tissue reveal regional boundaries.

a Normalised protein intensity of four example proteins mapped back to the original spatial positions within the atypical teratoid-rhabdoid tumour (AT/RT) tumour tissue at a resolution of 833 µm (n = 1) (a) and 350 µm (representative from three independent experiments) (b) with their corresponding Moran’s Index of spatial autocorrelation (I). Box in a represents the area analysed in an adjacent tissue section (b). Scale bar = 1 mm. Normalised protein intensities are scaled separately for each protein. Grey = not detected.