Fig. 2: Cross-species analysis of 6332 antimicrobial resistance genes, gene locations, and functions. | Nature Communications

Fig. 2: Cross-species analysis of 6332 antimicrobial resistance genes, gene locations, and functions.

From: Global pathogenomic analysis identifies known and candidate genetic antimicrobial resistance determinants in twelve species

Fig. 2

a Relationship between the number of species an AMR gene is observed in and tendency to be plasmid-encoded. b Enrichment of AMR gene functional categories in plasmid- over chromosomally-encoded genes and in multispecies over single species genes, based on log2 odds ratios (LORs). See Supplementary Data 3 for abbreviations. c Number of AMR genes shared between each pair of species, compared to species phylogenetic class. d Distribution of predicted gene locations and total occurrences per phylogenetic class for AMR genes appearing in at least 10 genomes of multiple classes. The three blaTEM cluster columns correspond to different sequence clusters identified by CD-HIT all related to TEM family beta-lactamases, with the first representing full variants and the others representing fragments.

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