Fig. 6: In vivo adhesion and biocompatibility of PolyLA-Na/PolyLA adhesive patch. | Nature Communications

Fig. 6: In vivo adhesion and biocompatibility of PolyLA-Na/PolyLA adhesive patch.

From: A self-stabilized and water-responsive deliverable coenzyme-based polymer binary elastomer adhesive patch for treating oral ulcer

Fig. 6

a Adhesion of PolyLA-Na/PolyLA patch on the wet surface of the rat buccal mucosa, gingiva, palate mucosa, and tongue; b Movement-resistant adhesion of PolyLA-Na/PolyLA-2-1 patch in vivo; c Adhesion of chitosan film in oral cavity; d Durable adhesion ability of PolyLA-Na/PolyLA-2-1 patch in oral cavity; e, f Live/Dead staining and cell viability of hGFs cells co-cultured with PolyLA-Na/PolyLA patch for 1 and 3 days (n = 4); g H&E staining of buccal mucosa tissue after attachment of PolyLA-Na/PolyLA patch for 12 h (n = 3 biologically independent samples in each group); h H&E staining of main organs after PolyLA-Na/PolyLA patch treatment for 8 days (n = 3 biologically independent samples in each group). (All presented data are mean values ± SD from the mean from n = 4 independent measurements on independent samples. All p values were calculated using a two-sided Student’s t test).

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