Fig. 3: Expression of the major Th transcription factors by in vitro cultured CD4+ T lymphocytes from NOD mice isolated and cohoused with 116C-NOD mice.
From: Mutual modulation of gut microbiota and the immune system in type 1 diabetes models

Expression of the transcription factors T-bet, RORγT, GATA3, and Foxp3 in T cells from NOD mice isolated (isoNOD T cells) and cohoused (coNOD T cells) cultured in vitro under the stimuli previously described in Fig. 2 (n = 7 for isoNOD and coNOD T cells in each culture condition). DP = double positive population for the markers in question and negative for the rest of the markers. Two independent experiments were performed (both depicted). Data are expressed as mean ± SD and analysed with two-way ANOVA test (two-sided) on rank-transformed data-values.