Fig. 4: The detailed interactions between MtbFtsEX and RipC.
From: Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis
a The RipC is bound to the ECD domain of FtsEX. The structures are represented by ribbon. Color scheme: FtsX is indicated in cornflower blue/rosy brown, FtsE is indicated in magenta/dark green. For RipC, α1 in plum, lip in purple, α2 in red, pro-rich linker in blue, the NlpC/P60 catalytic domain in cyan. b–d Interaction details (front view) of interface 1, 2 and 3 between FtsX and RipC. Critical residues are shown with sticks. e RipC binding assay of FtsX and RipC mutants from FtsX-RipC interface. In shorts, Kink-2A: the ECDFtsX kink region mutant D54A-R55A. Kink-3A: the ECDFtsX kink region mutant I51A-Y52A-L53A. kink-7A: the ECDFtsX kink region mutant R49A-A50A-I51A-Y52A-L53A-D54A-R55A. Each experiment was repeated three times independently with similar results. Source data are provided as a Source Data file.
