Fig. 5: Integration of 8 × 4 cross-point topography inside a 50 µm shank for in vivo LFP recordings. | Nature Communications

Fig. 5: Integration of 8 × 4 cross-point topography inside a 50 µm shank for in vivo LFP recordings.

From: Flexible switch matrix addressable electrode arrays with organic electrochemical transistor and pn diode technology

Fig. 5

a A micrograph of a 32-channel shank with 26 μm pixels and 40 μm pitch. In the inset, the flexibility of the shank is illustrated by wrapping the structure around a 1 mm pipette (n = 8 devices). b Implantation process of the multiplexer shank. The flexible shank is laminated on the exposed surface of the brain. A carrier glass pipette is anchored to the shank extension with a through-hole. A pipette is subsequently used to insert the shank and retracted to leave the fully flexible dual probe inserted inside the visual cortex of the brain. c Noise spectra of the OED–OECT stack acquired in saline within 0.1–100 Hz frequency range. d Local field potential waveform from the top 13 channels. The color map is expressed in arbitrary units as a function of LFP power within the 0.1–40 Hz frequency band and is added to illustrate the power decay of recorded LFPs as a function of distance (n = 3 implantations). e LFP power as a function of frequency within the 0.2–40 Hz frequency band. f H&E staining images were acquired 1 month after the probe implantation. The implantation zone is noted by an orange circle. The dashed orange circle delineates the implantation zone.

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