Fig. 1: Key characteristics of lead antibodies and schematic drawing of DONQ52. | Nature Communications

Fig. 1: Key characteristics of lead antibodies and schematic drawing of DONQ52.

From: Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease

Fig. 1

a Lead antibodies binding to Ba/F3 cells expressing various pHLA II as determined by flow cytometry. Gating strategy to determine the MFI is shown in Supplementary Fig. 11a. Data are from an assay performed in triplicates (n = 3). Heat map represents relative mean MFI (%) of antibodies (DQN0344xx and DQN0385ee: 0.5 μg/mL, Control Ab: 10 μg/mL) to DQN0139 (anti-HLA-DQ neutralizing antibody, 10 μg/mL). b Schematic drawing of DONQ52.

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