Table 2 Secondary metabolites (SMs) produced by A. fumigatus wild-type, ΔpexE, and ΔpexG

Brevianamide F

3.1 ± 0.2e7

2.3 ± 1.6e6

0.00

8.3 ± 0.5e6

0.00

Cycloprostatin A

0.00 ± 0.00

3.0 ± 0.8e6

0.01

5.7 ± 1.9e6

0.02

Cyclotryprostatin A

2.9 ± 1.9e6

0.00 ± 0.00

0.02

0.00 ± 0.00

0.02

Cyclotryprostatin C

0.00 ± 0.00

0.00 ± 0.00

ND

2.9 ± 0.9e8

0.01

Demethoxyfumitremorgin C

4.8 ± 2.1e6

2.8 ± 1.1e6

0.12

8.5 ± 0.7e7

0.00

Fumagillin

4.4 ± 1.0e7

0.00 ± 0.00

0.01

8.7 ± 0.9e7

0.00

Fumigaclavine C

0.00 ± 0.00

2.4 ± 0.4e6

0.00

9.3 ± 2.3e6

0.01

Fumiquinazoline A or B

2.3 ± 0.9e6

6.2 ± 4.8e6

0.15

1.5 ± 0.5e8

0.02

Fumiquinazoline E

3.2 ± 1.5e6

1.7 ± 0.7e6

0.12

8.8 ± 3.9e6

0.06

Fumiquinazoline F or G

1.7 ± 0.4e7

3.2 ± 2.8e7

0.23

5.8 ± 0.5e8

0.00

Fumitremorgin A

0.00 ± 0.00

2.1 ± 1.3e5

0.06

0.00 ± 0.00

ND

Fumitremorgin B

0.00 ± 0.00

0.00 ± 0.00

ND

2.3 ± 0.6e6

0.01

Fumitremorgin C

1.4 ± 0.6e7

1.7 ± 1.1e7

0.03

6.6 ± 1.8e8

0.01

Fungisporin

1.3 ± 0.2e7

0.00 ± 0.00

0.00

7.0 ± 04e6

0.05

Pseurotin A

1.5 ± 0.1e7

5.6 ± 5.2e6

0.05

1.8 ± 0.3e7

0.10

Pseurotin D

0.00 ± 0.00

5.7 ± 1.6e6

0.01

0.00 ± 0.00

ND

Pseurotin F2

0.00 ± 0.00

2.4 ± 2.4e6

0.11

3.1 ± 0.7e6

0.01

Pyripyropene A

4.6 ± 2.3e6

1.4 ± 0.5e6

0.06

2.8 ± 1.7e6

0.17

Pyripyropene E

0.00 ± 0.00

1.6 ± 1.3e6

0.08

1.0 ± 0.4e7

0.03

Pyripyropene F

0.00 ± 0.00

0.00 ± 0.00

ND

1.5 ± 0.8e6

0.04

Pyripyropene N

4.8 ± 0.2e6

1.1 ± 0.5e7

0.08

3.3 ± 1.4e6

0.11

Spirotryprostatin A

4.6 ± 1.8e7

2.0 ± 1.1e7

0.07

2.4 ± 0.3e8

0.00

Trypostatin A

1.2 ± 0.4e7

2.6 ± 1.7e6

0.02

9.7 ± 1.1e6

0.26

Trypostatin B

6.2 ± 1.3e6

6.3 ± 6.5e6

0.49

2.9 ± 0.8e8

0.01