Fig. 5: Enriched KEGG pathway and GO analysis of differential expressed genes between wildtype and knockout strains based on their functions.

a Enriched KEGG pathway terms of all DEG. b Enriched GO terms of upregulated genes. The x-axis is the enrich factor, which is the ratio of DEGs numbers annotated in the pathway term to all gene numbers annotated in the pathway term. The y-axis is the minus log10 scale of the adjusted p values [–log10 (adjusted p value)], which indicates the significant level of expression difference. Fisher’s exact test was used to test significance and adjusted by Benjamini and Hochberg. Source data are provided as a Source Data file.