Fig. 5: Atomic structure and DFT analysis of ferritin iron cores.
From: A natural biogenic nanozyme for scavenging superoxide radicals
a SOD-like activity of reconstituted HFn with gradient surface binding phosphate. The p value of Pi/Fe = 0.1, 0.2, 1 compared with Pi/Fe = 0 was 0.091, 0.435, 0.5339, respectively. b SOD-like activity of the 2-line ferrihydrite with gradient surface binding phosphate. The p value of Pi/Fe = 0.1, 0.2, 1 compared with Pi/Fe = 0 was 0.7172, 0.7761, 0.4216, respectively. The data in (a, b) are mean ± SD (n = 3 independent experiments); the significant difference was evaluated by the Two-way ANOVA with post-hoc Tukey HSD test; ns: non-significance, p > 0.05. c ICP-MS of P content and P/Fe ratios in the 2-line ferrihydrite with gradient surface binding phosphate; the data are presented as mean ± SD (n = 3 independent experiments). d, e XANES spectra of biomineralized HFn, pfFn, pyFn and relative reference materials. f Fourier-transformed magnitudes of the experimental Fe K-edge EXAFS signals of biomineralized HFn, pfFn, pyFn, and relative reference materials. g Proposed two possible reaction pathways for superoxide with products of H2O2 and O2 (main reaction) or O2 and H* (side reaction) and catalytic centers in Ferrihydrite and P-doped Ferrihydrite. h Reaction profiles with key intermediate structures and reaction energies (eV) for ferrihydrite. i Reaction profiles with key intermediate structures and reaction energies (eV) for P-doped ferrihydrite. Only important structural fragments were shown for clarity. Source data are provided as a Source Data file.
