Fig. 1: The OLFWT propeller structure and key regions of interest for amyloid formation. | Nature Communications

Fig. 1: The OLFWT propeller structure and key regions of interest for amyloid formation.

From: Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller

Fig. 1

Cartoon representation of OLFWT (PDB code 4WXS, [https://doi.org/10.2210/pdb4WXS/pdb] from N (blue) to C (red terminus). Ca2+, grey sphere. Na+, pink sphere. P1, P2, and P3 are predicted APRs, of which isolated peptides comprising P1 and P3 sequences form amyloid. *, positions of mutations (D380, I499) described in the manuscript.

Back to article page