Table 1 Baseline Patient Demographic and Clinical Characteristics

From: Bipolar androgen therapy plus nivolumab for patients with metastatic castration-resistant prostate cancer: the COMBAT phase II trial

 

N = 45

Age (years)

Median

69

(Range)

(51–86)

Race

Caucasian

39 (86.7%)

African-American

4 (8.9%)

Asian

1 (2.2%)

Hispanic

1 (2.2%)

Baseline PSA (ng/mL)

Median

57.6

(Range)

(5.4-457)

Gleason Sum

≤ 7

11 (24.4%)

8

8 (17.8%)

9

18 (40.0%)

10

5 (11.1%)

Unknown

3 (6.7%)

Visceral Disease

Yes

7 (15.6%)

No

38 (84.4%)

Lines of Prior Novel AR Targeted Therapy

1

21 (46.7%)

≥2

24 (53.3%)

Prior Taxane Chemotherapy

Yes

20 (44.4%)

No

25 (55.6%)

≥ 2 Novel AR Targeted Therapy AND Prior Taxane Chemotherapy

Yes

15 (33.3%)

No

30 (66.7%)

  1. N Number of Patients, AR Androgen Receptor, PSA Prostate-specific antigen