Fig. 2: Regional plots of credible sets fine-mapped in each GWAS locus. | Nature Communications

Fig. 2: Regional plots of credible sets fine-mapped in each GWAS locus.

From: GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region

Fig. 2

The regional plot of each significant locus of the Japanese GWAS for SSc is presented. Each dot represents each SNP colored by the posterior probability (pp). Lead SNPs highlighted in bold and SNPs with pp > 0.3 are specified in each graph. a FCGR/FCRL, (b) STAT4, (c) TNFAIP3, (d) IRF5, (e) AHNAK2-PLD4. The left y-axis indicates -log10 (p-value) and the right y-axis indicates recombination rate (cM/Mb). Approximate Bayesian factors calculated for each locus and 95% credible set was created based on posterior inclusion probabilities (PIPs). 1428 cases and 112,599 controls were included. Source data are provided as a Source Data file.

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