Fig. 4: Correlations between IgG binding levels at early and subsequent timepoints.

Violin plots showing the correlation between IgG levels at different timepoints across individuals for each protein. Each point represents the Pearson R correlation coefficient for a protein across individuals at two sampled ages. ABTs for which the R coefficient was negative are labelled. Proteins are grouped and coloured by their type, as displayed in Fig. 2. The data for each type is summarised by a violin plot with a horizontal line showing the median value. For each comparison between sampling ages, for each protein type, a two-tailed Wilcoxon rank sum test was used to assess whether the R values deviated from the null hypothesis of no correlation in IgG responses between sampling ages, with a Holm-Bonferroni correction for multiple testing applied within each panel. Significant deviations from this null hypothesis are annotated with p values above the corresponding plot. a Correlations between the IgG level in the maternal blood sample and the later samples. b Correlations between the IgG level in the sample taken at 6 mo and later samples. Source data are provided as a Source Data file.